The Brazilians reached the last four of the MTN8 on Sunday, but it came at a cost.
Despite beating SuperSport United 3-1, Mamelodi Sundowns suffered an injury to their main striker, Leonardo Castro.
It will be complicated for them going forward in the Caf Champions League, as new attacking signings Yannick Zakri and Sibusiso Vilakazi are cup-tied.
“I can do without Leo not playing in the PSL, but Champions League… I have lost [Katlego] Mashego, Lebohang Mokoena, [Cuthbert] Malajila, Mogakolodi [Ngele], Bongani [Zungu], Ramahlwe [Mphahlele] and [Asavela] Mbekile is injured… [he] dislocated shoulder,” said Mosimane.
“There are players on yellow cards that I have to worry about, so it is a big problem.
“I think he [Castro] will be out for the semi-final and I think we might finish the tournament without him because the injury was big. I hope he comes back for the final because I believe we will reach the final,” he concluded.